Cationic Lipid Content in Liposome-Encapsulated Nisin Improves Sustainable Bactericidal Activity against Streptococcus mutans
نویسندگان
چکیده
منابع مشابه
Cationic Lipid Content in Liposome-Encapsulated Nisin Improves Sustainable Bactericidal Activity against Streptococcus mutans
An oral infectious disease, dental caries, is caused by the cariogenic streptococci Streptococcus mutans. The expected preventive efficiency for prophylactics against dental caries is not yet completely observed. Nisin, a bacteriocin, has been demonstrated to be microbicidal against S. mutans, and liposome-encapsulated nisin improves preventive features that may be exploited for human oral heal...
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Nisin is a class I bacteriocin produced by Lactococcus lactis subsp. lactis [3]. It has been found to inhibit the viability of Grampositive bacteria. Bactericidal activity of nisin against S. mutans leads to inhibition of insoluble glucan formation, and nisin does not appear to be toxic to normal human gingival fibroblasts and epithelial cells [4,5]. Furthermore, Tong et al. [6] investigated th...
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background and objectives: the most common problems limiting the medical use of aminoglycosides have been the nephro- and oto-toxicities as well as the increasing bacterial resistance. encapsulation of drugs into liposomes enhances their efficacy while reducing their toxicities. the aim of this study was to evaluate the antimicrobial activity of free and liposomal amikacin. material and method...
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ژورنال
عنوان ژورنال: The Open Dentistry Journal
سال: 2016
ISSN: 1874-2106
DOI: 10.2174/1874210616021001360